Open AccessARWEN: a program to detect tRNA genes in metazoan mitochondrial nucleotide sequences
Author(s) -
Dean Laslett,
Björn Canbäck
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm573
Subject(s) - transfer rna , gene , biology , genetics , mitochondrial dna , genome , encode , computational biology , nucleotide , genetic code , rna
Mitochondrial genomes encode their own transfer RNAs (tRNAs). These are often degenerate in sequence and structure compared to tRNAs in their bacterial ancestors. This is one of the reasons why current tRNA gene predictor programs perform poorly identifying mitochondrial tRNA genes. As a consequence there is a need for a new program with the specific aim of predicting these tRNAs.
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