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Identification of linked regions using high-density SNP genotype data in linkage analysis
Author(s) -
Guohui Lin,
Zhanyong Wang,
Lusheng Wang,
YL Lau,
Wanling Yang
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm552
Subject(s) - identification (biology) , linkage (software) , snp , genotype , genetics , computational biology , biology , snp array , genetic linkage , computer science , single nucleotide polymorphism , gene , botany
With the knowledge of large number of SNPs in human genome and the fast development in high-throughput genotyping technologies, identification of linked regions in linkage analysis through allele sharing status determination will play an ever important role, while consideration of recombination fractions becomes unnecessary.

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