Identification of linked regions using high-density SNP genotype data in linkage analysis
Author(s) -
Guohui Lin,
Zhanyong Wang,
Lusheng Wang,
YL Lau,
Wanling Yang
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm552
Subject(s) - identification (biology) , linkage (software) , snp , genotype , genetics , computational biology , biology , snp array , genetic linkage , computer science , single nucleotide polymorphism , gene , botany
With the knowledge of large number of SNPs in human genome and the fast development in high-throughput genotyping technologies, identification of linked regions in linkage analysis through allele sharing status determination will play an ever important role, while consideration of recombination fractions becomes unnecessary.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom