Carbon-fate maps for metabolic reactions | Zendy

Fangping Mu | Zendy; Robert F. Williams | Zendy; Clifford J. Ünkefer | Zendy; Pat J. Unkefer | Zendy; James R. Faeder | Zendy; William S. Hlavacek | Zendy

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Carbon-fate maps for metabolic reactions

Author(s) -

Fangping Mu,

Robert F. Williams,

Clifford J. Ünkefer,

Pat J. Unkefer,

James R. Faeder,

William S. Hlavacek

Publication year - 2007

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm498

Subject(s) - bijection , isotopomers , identifier , computer science , consistency (knowledge bases) , carbon fibers , software , isotopes of carbon , set (abstract data type) , chemistry , molecule , programming language , algorithm , mathematics , artificial intelligence , total organic carbon , organic chemistry , discrete mathematics , composite number

Stable isotope labeling of small-molecule metabolites (e.g. (13)C-labeling of glucose) is a powerful tool for characterizing pathways and reaction fluxes in a metabolic network. Analysis of isotope labeling patterns requires knowledge of the fates of individual atoms and moieties in reactions, which can be difficult to collect in a useful form when considering a large number of enzymatic reactions.

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