QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations
Author(s) -
Jian Yang,
Chengcheng Hu,
Han Hu,
Rongdong Yu,
Zhen Xia,
Xiuzi Ye,
Jun Zhu
Publication year - 2008
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm494
Subject(s) - quantitative trait locus , unix , epistasis , genetic architecture , graphical user interface , computer science , software , biology , inbred strain , computational biology , genetics , operating system , gene
QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines. It can simultaneously map quantitative trait loci (QTL) with individual effects, epistasis and QTL-environment interaction. Currently, it is able to handle data from F(2), backcross, recombinant inbred lines and double-haploid populations, as well as populations from specific mating designs (immortalized F(2) and BC(n)F(n) populations). The Windows version of QTLNetwork was developed with a graphical user interface. Alternatively, the command-line versions have the facility to be run in other prevalent operating systems, such as Linux, Unix and MacOS.
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