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Biclustering as a method for RNA local multiple sequence alignment
Author(s) -
Shu Wang,
Robin R. Gutell,
Daniel P. Miranker
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm485
Subject(s) - biclustering , multiple sequence alignment , benchmark (surveying) , cluster analysis , computer science , sequence alignment , suite , sequence (biology) , hierarchical clustering , data mining , set (abstract data type) , alignment free sequence analysis , smith–waterman algorithm , artificial intelligence , biology , correlation clustering , genetics , cartography , cure data clustering algorithm , history , archaeology , peptide sequence , gene , programming language , geography
Biclustering is a clustering method that simultaneously clusters both the domain and range of a relation. A challenge in multiple sequence alignment (MSA) is that the alignment of sequences is often intended to reveal groups of conserved functional subsequences. Simultaneously, the grouping of the sequences can impact the alignment; precisely the kind of dual situation biclustering is intended to address.

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