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miniTUBA: medical inference by network integration of temporal data using Bayesian analysis
Author(s) -
Zuoshuang Xiang,
Rebecca M. Minter,
Xiaoming Bi,
Peter Woolf,
Yongqun He
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm372
Subject(s) - computer science , inference , dynamic bayesian network , bayesian network , machine learning , pipeline (software) , artificial intelligence , data mining , causal inference , bayesian probability , variable order bayesian network , software , bayesian inference , economics , econometrics , programming language
Many biomedical and clinical research problems involve discovering causal relationships between observations gathered from temporal events. Dynamic Bayesian networks are a powerful modeling approach to describe causal or apparently causal relationships, and support complex medical inference, such as future response prediction, automated learning, and rational decision making. Although many engines exist for creating Bayesian networks, most require a local installation and significant data manipulation to be practical for a general biologist or clinician. No software pipeline currently exists for interpretation and inference of dynamic Bayesian networks learned from biomedical and clinical data.

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