An approach to predict transcription factor DNA binding site specificity based upon gene and transcription factor functional categorization | Zendy

Ziliang Qian | Zendy; Lingyi Lu | Zendy; Xiaojun Liu | Zendy; YuDong Cai | Zendy; Yixue Li | Zendy

Open Access

An approach to predict transcription factor DNA binding site specificity based upon gene and transcription factor functional categorization

Author(s) -

Ziliang Qian,

Lingyi Lu,

Xiaojun Liu,

YuDong Cai,

Yixue Li

Publication year - 2007

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm348

Subject(s) - transcription factor , dna binding site , computational biology , categorization , genetics , gene , dna , biology , transcription (linguistics) , taf2 , general transcription factor , sp3 transcription factor , factor (programming language) , promoter , computer science , gene expression , enhancer , artificial intelligence , linguistics , philosophy , programming language

To understand transcription regulatory mechanisms, it is indispensable to investigate transcription factor (TF) DNA binding preferences. We noted that the generally acknowledged information of functional annotations of TFs as well as that of their target genes should provide useful hints in determining TF DNA binding preferences.

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