Different packing of external residues can explain differences in the thermostability of proteins from thermophilic and mesophilic organisms
Author(s) -
Anna V. Glyakina,
Sergiy O. Garbuzynskiy,
Michail Yu. Lobanov,
Oxana V. Galzitskaya
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm345
Subject(s) - thermostability , thermophile , mesophile , chemistry , biology , biochemistry , genetics , enzyme , bacteria
Understanding the basis of protein stability in thermophilic organisms raises a general question: what structural properties of proteins are responsible for the higher thermostability of proteins from thermophilic organisms compared to proteins from mesophilic organisms?
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