POODLE-S: web application for predicting protein disorder by using physicochemical features and reduced amino acid set of a position-specific scoring matrix
Author(s) -
Kana Shimizu,
Shuichi Hirose,
Tamotsu Noguchi
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm330
Subject(s) - amino acid , position (finance) , set (abstract data type) , matrix (chemical analysis) , web browser , computational biology , computer science , biology , chemistry , world wide web , genetics , chromatography , the internet , finance , programming language , economics
Protein disorder is characterized by a lack of a stable 3D structure, and is considered to be involved in a number of important protein functions such as regulatory and signalling events. We developed a web application, the POODLE-S, which predicts the disordered region from amino acid sequences by using physicochemical features and reduced amino acid set of a position-specific scoring matrix.
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