VIPER: an advanced software package to support high-throughput LC-MS peptide identification | Zendy

Matthew Monroe | Zendy; Nikola Tolić | Zendy; Navdeep Jaitly | Zendy; Jason L. Shaw | Zendy; Joshua Adkins | Zendy; Richard Smith | Zendy

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VIPER: an advanced software package to support high-throughput LC-MS peptide identification

Author(s) -

Matthew Monroe,

Nikola Tolić,

Navdeep Jaitly,

Jason L. Shaw,

Joshua Adkins,

Richard Smith

Publication year - 2007

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm281

Subject(s) - pipeline (software) , computer science , software , identification (biology) , throughput , data mining , viper , chemistry , operating system , biology , venom , biochemistry , botany , wireless

The accurate mass and time (AMT) tag approach is used for analysis of large scale experiments by combining information generated over multiple datasets and instrument types. The VIPER software package is one of the key components of the data processing pipeline and implements automated algorithms to discover LC-MS features, align and match these LC-MS features to a database of peptides previously identified in LC-MS/MS analyses, and identify and quantify pairs of isotopically labeled peptides.

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