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PLMaddon: a power-law module for the Matlab™ SBToolbox
Author(s) -
Julio Vera,
Cheng Sun,
Yvonne Oertel,
Olaf Wolkenhauer
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm245
Subject(s) - ode , toolbox , mit license , computer science , matlab , logarithm , set (abstract data type) , power law , robustness (evolution) , ordinary differential equation , software , theoretical computer science , law , mathematics , mathematical optimization , computational science , differential equation , programming language , mathematical analysis , biochemistry , statistics , chemistry , political science , gene
PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-law's logarithmic gains and sensitivities.

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