Automated Improvement of Domain ANnotations using context analysis of domain arrangements (AIDAN) | Zendy

Francois Beaussart | Zendy; January Weiner | Zendy; Erich BornbergBauer | Zendy

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Automated Improvement of Domain ANnotations using context analysis of domain arrangements (AIDAN)

Author(s) -

Francois Beaussart,

January Weiner,

Erich BornbergBauer

Publication year - 2007

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm240

Subject(s) - domain (mathematical analysis) , annotation , computer science , context (archaeology) , information retrieval , protein domain , sequence (biology) , data science , artificial intelligence , biology , genetics , mathematical analysis , mathematics , gene , paleontology

Since protein domains are the units of evolution, databases of domain signatures such as ProDom or Pfam enable both a sensitive and selective sequence analysis. However, manually curated databases have a low coverage and automatically generated ones often miss relationships which have not yet been discovered between domains or cannot display similarities between domains which have drifted apart.

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