Genetdes: automatic design of transcriptional networks | Zendy

Guillermo Rodrigo | Zendy; Javier Carrera | Zendy; Alfonso Jaramillo | Zendy

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Genetdes: automatic design of transcriptional networks

Author(s) -

Guillermo Rodrigo,

Javier Carrera,

Alfonso Jaramillo

Publication year - 2007

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm237

Subject(s) - sbml , computer science , software , theoretical computer science , biological network , software tool , systems biology , simulated annealing , electronic circuit , transcription (linguistics) , gene regulatory network , distributed computing , computational biology , gene , algorithm , programming language , biology , markup language , genetics , gene expression , engineering , linguistics , philosophy , xml , electrical engineering , operating system

The rational design of biological networks with prescribed functions is limited to gene circuits of a few genes. Larger networks involve complex interactions with many parameters and the use of automated computational tools can be very valuable. We propose a new tool to design transcriptional networks with targeted behavior that could be used to better understand the design principles of genetic circuits.

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