Open AccessA network-based method for target selection in metabolic networks
Author(s) -
Roger Guimerà,
Marta SalesPardo,
Luı́s A. Nunes Amaral
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm150
Subject(s) - identification (biology) , computational biology , computer science , metabolic network , biological network , selection (genetic algorithm) , genome , systems biology , biology , drug discovery , machine learning , bioinformatics , genetics , gene , botany
The lack of new antimicrobials, combined with increasing microbial resistance to old ones, poses a serious threat to public health. With hundreds of genomes sequenced, systems biology promises to help in solving this problem by uncovering new drug targets.
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