Meta-analysis of gene expression data: a predictor-based approach
Author(s) -
Irit Fishel,
Alon Kaufman,
Eytan Ruppin
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm149
Subject(s) - microarray analysis techniques , robustness (evolution) , computer science , set (abstract data type) , microarray databases , microarray , gene chip analysis , data mining , data set , computational biology , gene , artificial intelligence , biology , gene expression , genetics , programming language
With the increasing availability of cancer microarray data sets there is a growing need for integrative computational methods that evaluate multiple independent microarray data sets investigating a common theme or disorder. Meta-analysis techniques are designed to overcome the low sample size typical to microarray experiments and yield more valid and informative results than each experiment separately.
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