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SQUINT: a multiple alignment program and editor
Author(s) -
Matthew Goode,
Allen G. Rodrigo
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm128
Subject(s) - multiple sequence alignment , computer science , block (permutation group theory) , software , sequence alignment , sequence (biology) , file format , variety (cybernetics) , computer graphics (images) , artificial intelligence , programming language , peptide sequence , biology , mathematics , biochemistry , genetics , geometry , gene
SQUINT is a sequence alignment tool, and combines both automated progressive sequence alignment with facilities for manual editing. The program imports nucleotide or amino acid sequence multiple alignment files in standard formats, and permits users to view two translations of the same multiple alignment simultaneously. Edits in one view are instantaneously reflected in the other, and the scoring cost of the changes are shown in real-time. Progressive multiple alignments, using a variety of alignment parameters, can be performed on any block of sequences, including blocks embedded in the existing alignment.

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