SherLoc: high-accuracy prediction of protein subcellular localization by integrating text and protein sequence data
Author(s) -
Hagit Shatkay,
Annette Höglund,
Scott T. Brady,
Torsten Blum,
Pierre Dönnes,
Oliver Kohlbacher
Publication year - 2007
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btm115
Subject(s) - computer science , sequence (biology) , protein sequencing , artificial intelligence , computational biology , protein subcellular localization prediction , data mining , pattern recognition (psychology) , peptide sequence , biology , genetics , gene
Knowing the localization of a protein within the cell helps elucidate its role in biological processes, its function and its potential as a drug target. Thus, subcellular localization prediction is an active research area. Numerous localization prediction systems are described in the literature; some focus on specific localizations or organisms, while others attempt to cover a wide range of localizations.
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