rh_tsp_map3.0: end-to-end radiation hybrid mapping with improved speed and quality control | Zendy

Alejandro A. Schäffer | Zendy; Edward Stallknecht Rice | Zendy; William J. Cook | Zendy; Richa Agarwala | Zendy

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rh_tsp_map3.0: end-to-end radiation hybrid mapping with improved speed and quality control

Author(s) -

Alejandro A. Schäffer,

Edward Stallknecht Rice,

William J. Cook,

Richa Agarwala

Publication year - 2007

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm077

Subject(s) - end to end principle , computer science , end milling , software , end user , quality (philosophy) , artificial intelligence , operating system , physics , materials science , quantum mechanics , metallurgy , machining

rh_tsp_map is a software package for computing radiation hybrid (RH) maps and for integrating physical and genetic maps. It solves the central mapping instances by reducing them to the traveling salesman problem (TSP) and using a modification of the CONCORDE package to solve the TSP instances. We present some of the features added between the initial rh_tsp_map version 1.0 and the current version 3.0, emphasizing the automation of many steps and addition of various checks designed to find problems with the input data. Iterations of improved input data followed by fast re-computation of the maps improves the quality of the final maps.

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