Clustering by common friends finds locally significant proteins mediating modules | Zendy

Bill Andreopoulos | Zendy; Aijun An | Zendy; Xiaogang Wang | Zendy; Michalis Faloutsos | Zendy; Michael Schroeder | Zendy

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Clustering by common friends finds locally significant proteins mediating modules

Author(s) -

Bill Andreopoulos,

Aijun An,

Xiaogang Wang,

Michalis Faloutsos,

Michael Schroeder

Publication year - 2007

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btm064

Subject(s) - cluster analysis , computer science , precision and recall , cluster (spacecraft) , domain (mathematical analysis) , computational biology , function (biology) , cytoplasm , set (abstract data type) , data mining , theoretical computer science , biology , genetics , artificial intelligence , mathematics , computer network , mathematical analysis , programming language

Much research has been dedicated to large-scale protein interaction networks including the analysis of scale-free topologies, network modules and the relation of domain-domain to protein-protein interaction networks. Identifying locally significant proteins that mediate the function of modules is still an open problem.

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