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AGScan: a pluggable microarray image quantification software based on the ImageJ library
Author(s) -
R. Cathelin,
Fabrice Lopez,
Ch. Klopp
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl564
Subject(s) - computer science , plug in , software , grid , data mining , extension (predicate logic) , mac os , open source , metadata , os x , image (mathematics) , computer graphics (images) , operating system , embedded system , artificial intelligence , programming language , geometry , mathematics
Many different programs are available to analyze microarray images. Most programs are commercial packages, some are free. In the latter group only few propose automatic grid alignment and batch mode. More often than not a program implements only one quantification algorithm. AGScan is an open source program that works on all major platforms. It is based on the ImageJ library [Rasband (1997-2006)] and offers a plug-in extension system to add new functions to manipulate images, align grid and quantify spots. It is appropriate for daily laboratory use and also as a framework for new algorithms.

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