Open AccessssSNPer: identifying statistically similar SNPs to aid interpretation of genetic association studies
Author(s) -
Dale R. Nyholt
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl518
Subject(s) - international hapmap project , single nucleotide polymorphism , snp , identification (biology) , genetic association , interpretation (philosophy) , association (psychology) , genome wide association study , biology , computational biology , computer science , genetics , genotype , gene , psychology , ecology , psychotherapist , programming language
ssSNPer is a novel user-friendly web interface that provides easy determination of the number and location of untested HapMap SNPs, in the region surrounding a tested HapMap SNP, which are statistically similar and would thus produce comparable and perhaps more significant association results. Identification of ssSNPs can have crucial implications for the interpretation of the initial association results and the design of follow-up studies.
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