Predicted function of the vaccinia virus G5R protein | Zendy

Melissa Da Silva | Zendy; Ling Shen | Zendy; Vasily Tcherepanov | Zendy; Cristalle N. Watson | Zendy; Chris Upton | Zendy

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Predicted function of the vaccinia virus G5R protein

Author(s) -

Melissa Da Silva,

Ling Shen,

Vasily Tcherepanov,

Cristalle N. Watson,

Chris Upton

Publication year - 2006

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btl506

Subject(s) - vaccinia , virology , virus , function (biology) , biology , orthopoxvirus , computational biology , computer science , genetics , gene , recombinant dna

Of the approximately 200 proteins that have been identified for the vaccinia virus (VACV) genome, many are currently listed as having an unknown function, and seven of these are also found in all other poxvirus genomes that have been sequenced. The G5R protein of VACV is included in this list, and to date, very little is known about this essential and highly conserved protein. Conventional similarity searches of protein databases do not identify significantly similar proteins, and experimental approaches have been unsuccessful at determining protein function.

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