GenoProfiler: batch processing of high-throughput capillary fingerprinting data
Author(s) -
Frank M. You,
MingCheng Luo,
Yong Q. Gu,
Gerard R. Lazo,
Karin R. Deal,
Jan Dvořák,
Olin D. Anderson
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl494
Subject(s) - fingerprint (computing) , computer science , software , fragment (logic) , throughput , capillary electrophoresis , dna profiling , batch processing , operating system , programming language , chromatography , chemistry , artificial intelligence , dna , biochemistry , wireless
High-throughput content fingerprinting techniques employing capillary electrophoresis place new demands on the editing of fingerprint files for the downstream contig assembly program, FPC. A cross-platform software application, GenoProfiler, was developed for automated editing of sized fingerprinting profiles generated by the ABI Genetic Analyzers. The batch-processing module extracts the sized fragment information directly from the ABI raw trace files, or from data files exported from GeneMapper or other size calling software, removes the background noise and undesired fragments, and generates fragment size files compatible with the FPC software.
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