Tropical—parameter estimation and simulation of reaction–diffusion models based on spatio-temporal microscopy images | Zendy

Markus Ulrich | Zendy; Constantin Kappel | Zendy; Joël Beaudouin | Zendy; Stefan Hezel | Zendy; Jochen Ulrich | Zendy; Roland Eils | Zendy

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Tropical—parameter estimation and simulation of reaction–diffusion models based on spatio-temporal microscopy images

Author(s) -

Markus Ulrich,

Constantin Kappel,

Joël Beaudouin,

Stefan Hezel,

Jochen Ulrich,

Roland Eils

Publication year - 2006

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btl456

Subject(s) - photobleaching , microscopy , diffusion , biological system , software , tropics , estimation theory , computer science , statistical physics , fluorescence , algorithm , optics , physics , biology , ecology , thermodynamics , programming language

Tropical is a software for simulation and parameter estimation of reaction-diffusion models. Based on spatio-temporal microscopy images, Tropical estimates reaction and diffusion coefficients for user-defined models. Tropical allows the investigation of systems with an inhomogeneous distribution of molecules, making it well suited for quantitative analyses of microscopy experiments such as fluorescence recovery after photobleaching (FRAP).

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