A suite of algorithms for the comprehensive analysis of complex protein mixtures using high-resolution LC-MS
Author(s) -
Matthew Bellew,
Marc Coram,
Matthew Fitzgibbon,
Mark Igra,
Tim R Randolph,
Pei Wang,
Damon May,
Jimmy K. Eng,
Ruihua Fang,
Chenwei Lin,
Jinzhi Chen,
David R. Goodlett,
Jeffrey R. Whiteaker,
Amanda G. Paulovich,
Martin McIntosh
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl276
Subject(s) - software suite , computer science , software , suite , scripting language , visualization , data mining , mit license , workbench , file format , resolution (logic) , open source software , algorithm , artificial intelligence , programming language , archaeology , history
Comparing two or more complex protein mixtures using liquid chromatography mass spectrometry (LC-MS) requires multiple analysis steps to locate and quantitate natural peptides within a single experiment and to align and normalize findings across multiple experiments.
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