Open AccessACE-it: a tool for genome-wide integration of gene dosage and RNA expression data
Author(s) -
Wessel N. van Wieringen,
Jeroen A.M. Beliën,
Sjoerd J. Vosse,
Eskeatnaf Mulugeta,
Bauke Ylstra
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl269
Subject(s) - gene dosage , gene expression , gene , computational biology , rna , biology , genome , genetics
We describe a tool, called ACE-it (Array CGH Expression integration tool). ACE-it links the chromosomal position of the gene dosage measured by array CGH to the genes measured by the expression array. ACE-it uses this link to statistically test whether gene dosage affects RNA expression.
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