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Annotating proteins by mining protein interaction networks
Author(s) -
Mustafa Kıraç,
Gültekin Özsoyoğlu,
Jiong Yang
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl221
Subject(s) - computer science , probabilistic logic , protein function prediction , set (abstract data type) , data mining , a priori and a posteriori , annotation , precision and recall , tree (set theory) , suffix , suffix tree , function (biology) , protein function , machine learning , information retrieval , artificial intelligence , data structure , gene , biology , programming language , mathematical analysis , biochemistry , philosophy , linguistics , mathematics , epistemology , evolutionary biology
In general, most accurate gene/protein annotations are provided by curators. Despite having lesser evidence strengths, it is inevitable to use computational methods for fast and a priori discovery of protein function annotations. This paper considers the problem of assigning Gene Ontology (GO) annotations to partially annotated or newly discovered proteins.

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