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Dynamical analysis of a generic Boolean model for the control of the mammalian cell cycle
Author(s) -
Adrien Fauré,
Aurélien Naldi,
Claudine Chaouiya,
Denis Thieffry
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl210
Subject(s) - computer science , asynchronous communication , theoretical computer science , verifiable secret sharing , xml , software , dynamical systems theory , biological network , core model , boolean network , dynamical system (definition) , logical data model , state (computer science) , distributed computing , boolean function , algorithm , data modeling , programming language , software engineering , computational biology , mathematics , biology , computer network , mathematical analysis , physics , set (abstract data type) , quantum mechanics , operating system
To understand the behaviour of complex biological regulatory networks, a proper integration of molecular data into a full-fledge formal dynamical model is ultimately required. As most available data on regulatory interactions are qualitative, logical modelling offers an interesting framework to delineate the main dynamical properties of the underlying networks.

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