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Distance-based clustering of CGH data
Author(s) -
Jun Liu,
Jaaved Mohammed,
James F. Carter,
Sanjay Ranka,
Tamer Kahveci,
Michael Baudis
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl185
Subject(s) - cluster analysis , pairwise comparison , similarity (geometry) , cosine similarity , population , centroid , computer science , correlation , mathematics , data mining , artificial intelligence , medicine , geometry , environmental health , image (mathematics)
We consider the problem of clustering a population of Comparative Genomic Hybridization (CGH) data samples. The goal is to develop a systematic way of placing patients with similar CGH imbalance profiles into the same cluster. Our expectation is that patients with the same cancer types will generally belong to the same cluster as their underlying CGH profiles will be similar.

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