Ribosomal RNA as molecular barcodes: a simple correlation analysis without sequence alignment | Zendy

Ka Hou Chu | Zendy; C. P. Li | Zendy; Ji Qi | Zendy

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Ribosomal RNA as molecular barcodes: a simple correlation analysis without sequence alignment

Author(s) -

Ka Hou Chu,

C. P. Li,

Ji Qi

Publication year - 2006

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btl146

Subject(s) - phylogenetic tree , biology , ribosomal rna , computational biology , sequence (biology) , tree (set theory) , sequence analysis , taxon , multiple sequence alignment , taxonomic rank , sequence alignment , genetics , gene , paleontology , combinatorics , mathematics , peptide sequence

We explored the feasibility of using unaligned rRNA gene sequences as DNA barcodes, based on correlation analysis of composition vectors (CVs) derived from nucleotide strings. We tested this method with seven rRNA (including 12, 16, 18, 26 and 28S) datasets from a wide variety of organisms (from archaea to tetrapods) at taxonomic levels ranging from class to species.

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