IWoCS: analyzing ribosomal intergenic transcribed spacers configuration and taxonomic relationships | Zendy

Giuseppe D’Auria | Zendy; Ravindra Pushker | Zendy; Francisco Rodrı́guez-Valera | Zendy

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IWoCS: analyzing ribosomal intergenic transcribed spacers configuration and taxonomic relationships

Author(s) -

Giuseppe D’Auria,

Ravindra Pushker,

Francisco Rodrı́guez-Valera

Publication year - 2006

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btk033

Subject(s) - biology , intergenic region , typing , ribosomal rna , dominance (genetics) , ribosomal intergenic spacer analysis , genetics , computational biology , internal transcribed spacer , gene , genome

Lately the use of 16S-23S Intergenic Transcribed Spacer (ITS) sequences for bacterial typing purposes has increased. The presence of conserved regions like tRNA genes or boxes together with hypervariable regions allows performing intraspecific discrimination of very close bacterial strains. On the other hand this mosaic of variability makes the ITS a sequence difficult to analyze and compare.

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