Short fuzzy tandem repeats in genomic sequences, identification, and possible role in regulation of gene expression
Author(s) -
Valentina Boeva,
Mireille Régnier,
Dmitri Papatsenko,
Vsevolod J. Makeev
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btk032
Subject(s) - enhancer , tandem repeat , computational biology , coding (social sciences) , gene , genome , biology , drosophila melanogaster , coding region , computer science , regulatory sequence , identification (biology) , genetics , regulation of gene expression , transcription factor , mathematics , statistics , botany
Genomic sequences are highly redundant and contain many types of repetitive DNA. Fuzzy tandem repeats (FTRs) are of particular interest. They are found in regulatory regions of eukaryotic genes and are reported to interact with transcription factors. However, accurate assessment of FTR occurrences in different genome segments requires specific algorithm for efficient FTR identification and classification.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom