eQTL Explorer: integrated mining of combined genetic linkage and expression experiments
Author(s) -
Michael Mueller,
Anuj Goel,
Manjula Thimma,
Nicholas J. Dickens,
Timothy J. Aitman,
Jonathan Mangion
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btk007
Subject(s) - expression quantitative trait loci , linkage (software) , computational biology , expression (computer science) , computer science , data mining , genetic linkage , biology , genetics , gene , genotype , single nucleotide polymorphism , programming language
The development of computational resources to visualize and explore data from combined genome-wide expression and linkage studies is essential for the development of testable hypotheses. eQTL Explorer stores expression profiles, linkage data and information from external sources in a relational database and enables simultaneous visualization and intuitive interpretation of the combined data via a Java graphical interface. eQTL Explorer provides a new and powerful tool to interrogate these very large and complex datasets.
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