Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae | Zendy

Xiang Guo | Zendy; Kay Tatsuoka | Zendy; Rongxiang Liu | Zendy

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Histone acetylation and transcriptional regulation in the genome of Saccharomyces cerevisiae

Author(s) -

Xiang Guo,

Kay Tatsuoka,

Rongxiang Liu

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti823

Subject(s) - biology , genetics , histone , transcription factor , histone code , acetylation , computational biology , gene , nucleosome

In eukaryotic genomes, histone acetylation and thereafter departure from the chromatin are essential for gene transcription initiation. Because gene transcription is tightly regulated by transcription factors, there are some speculations on the cooperation of histone acetylation and transcription factor binding. However, systematic statistical analyses of this relationship on a genomic scale have not been reported.

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