Open AccessHaplotype-based linkage disequilibrium mapping via direct data mining
Author(s) -
Jing Li,
Tao Jiang
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti732
Subject(s) - linkage disequilibrium , haplotype , linkage (software) , disequilibrium , computer science , haplotype estimation , data mining , computational biology , genetics , biology , allele , gene , medicine , ophthalmology
With the availability of large-scale, high-density single-nucleotide polymorphism markers and information on haplotype structures and frequencies, a great challenge is how to take advantage of haplotype information in the association mapping of complex diseases in case-control studies.
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