Design of long oligonucleotide probes for functional gene detection in a microbial community | Zendy

WonHyong Chung | Zendy; SungKeun Rhee | Zendy; XiuFeng Wan | Zendy; JinWoo Bae | Zendy; ZheXue Quan | Zendy; Yong-Ha Park | Zendy

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Design of long oligonucleotide probes for functional gene detection in a microbial community

Author(s) -

WonHyong Chung,

SungKeun Rhee,

XiuFeng Wan,

JinWoo Bae,

ZheXue Quan,

Yong-Ha Park

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti673

Subject(s) - oligonucleotide , computational biology , biology , sequence (biology) , gene , dna microarray , oligomer restriction , hierarchical clustering , gene cluster , sequence analysis , genetics , cluster analysis , computer science , gene expression , machine learning

Analysis of the functions of microorganisms and their dynamics in the environment is essential for understanding microbial ecology. For analysis of highly similar sequences of a functional gene family using microarrays, the previous long oligonucleotide probe design strategies have not been useful in generating probes.

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