Oligonucleotide arrays: information from replication and spatial structure
Author(s) -
Graham Upton,
Julie C. Lloyd
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti668
Subject(s) - gene chip analysis , computer science , replication (statistics) , computational biology , genome , dna microarray , biology , gene , data mining , genetics , gene expression , virology
The introduction of oligonucleotide DNA arrays has resulted in much debate concerning appropriate models for the measurement of gene expression. By contrast, little account has been taken of the possibility of identifying the physical imperfections in the raw data.
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