Open AccessData pre-processing in liquid chromatography-mass spectrometry-based proteomics
Author(s) -
Xiang Zhang,
John M. Asara,
Jiří Adamec,
Mourad Ouzzani,
Ahmed K. Elmagarmid
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti660
Subject(s) - mass spectrometry , chromatography , proteomics , liquid chromatography–mass spectrometry , chemistry , computer science , biochemistry , gene
In a liquid chromatography-mass spectrometry (LC-MS)-based expressional proteomics, multiple samples from different groups are analyzed in parallel. It is necessary to develop a data mining system to perform peak quantification, peak alignment and data quality assurance.
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