DBToolkit: processing protein databases for peptide-centric proteomics | Zendy

Lennart Martens | Zendy; Joël Vandekerckhove | Zendy; Kris Gevaert | Zendy

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DBToolkit: processing protein databases for peptide-centric proteomics

Author(s) -

Lennart Martens,

Joël Vandekerckhove,

Kris Gevaert

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti588

Subject(s) - computer science , database , sequence database , proteomics , database search engine , fragmentation (computing) , sequence (biology) , mascot , protein sequencing , peptide , identification (biology) , peptide sequence , information retrieval , data mining , search engine , chemistry , programming language , biology , biochemistry , botany , political science , law , gene

DBToolkit is a user-friendly, easily extensible tool that allows the processing of protein sequence databases to peptide-centric sequence databases. This processing is primarily aimed at enhancing the useful information content of these databases for use as optimized search spaces for efficient identification of peptide fragmentation spectra obtained by mass spectrometry. In addition, DBToolkit can be used to reliably solve a range of other typical tasks in processing sequence databases.

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