MatInspector and beyond: promoter analysis based on transcription factor binding sites | Zendy

Kerstin Cartharius | Zendy; Kornelie Frech | Zendy; Korbinian Grote | Zendy; Bernward Klocke | Zendy; Manuela Haltmeier | Zendy; Andreas Klingenhoff | Zendy; Matthias Frisch | Zendy; M. Bayerlein | Zendy; Thomas Werner | Zendy

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MatInspector and beyond: promoter analysis based on transcription factor binding sites

Author(s) -

Kerstin Cartharius,

Kornelie Frech,

Korbinian Grote,

Bernward Klocke,

Manuela Haltmeier,

Andreas Klingenhoff,

Matthias Frisch,

M. Bayerlein,

Thomas Werner

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti473

Subject(s) - promoter , computational biology , dna binding site , computer science , transcription factor , biology , genetics , binding site , gene , data mining , gene expression

Promoter analysis is an essential step on the way to identify regulatory networks. A prerequisite for successful promoter analysis is the prediction of potential transcription factor binding sites (TFBS) with reasonable accuracy. The next steps in promoter analysis can be tackled only with reliable predictions, e.g. finding phylogenetically conserved patterns or identifying higher order combinations of sites in promoters of co-regulated genes.

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