PROFcon: novel prediction of long-range contacts | Zendy

Marco Punta | Zendy; Burkhard Rost | Zendy

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PROFcon: novel prediction of long-range contacts

Author(s) -

Marco Punta,

Burkhard Rost

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti454

Subject(s) - protein structure prediction , protein secondary structure , protein structure , computer science , contrast (vision) , sequence (biology) , range (aeronautics) , artificial intelligence , biological system , pattern recognition (psychology) , biology , materials science , genetics , biochemistry , composite material

Despite the continuing advance in the experimental determination of protein structures, the gap between the number of known protein sequences and structures continues to increase. Prediction methods can bridge this sequence-structure gap only partially. Better predictions of non-local contacts between residues could improve comparative modeling, fold recognition and could assist in the experimental structure determination.

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