pFind: a novel database-searching software system for automated peptide and protein identification via tandem mass spectrometry | Zendy

Dongxiang Li | Zendy; Yan Fu | Zendy; Ren Sun | Zendy; Charles X. Ling | Zendy; Yanjie Wei | Zendy; Hui Zhou | Zendy; Rong Zeng | Zendy; Qiang Yang | Zendy; SiMin He | Zendy; Wen Gao | Zendy

Open Access

pFind: a novel database-searching software system for automated peptide and protein identification via tandem mass spectrometry

Author(s) -

Dongxiang Li,

Yan Fu,

Ren Sun,

Charles X. Ling,

Yanjie Wei,

Hui Zhou,

Rong Zeng,

Qiang Yang,

SiMin He,

Wen Gao

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti439

Subject(s) - computer science , usability , software , xml , database , tandem mass spectrometry , proteomics , identification (biology) , database search engine , tandem mass tag , data mining , mass spectrometry , information retrieval , quantitative proteomics , programming language , operating system , chemistry , search engine , chromatography , biology , biochemistry , botany , gene

Research in proteomics requires powerful database-searching software to automatically identify protein sequences in a complex protein mixture via tandem mass spectrometry. In this paper, we describe a novel database-searching software system called pFind (peptide/protein Finder), which employs an effective peptide-scoring algorithm that we reported earlier. The pFind server is implemented with the C++ STL, .Net and XML technologies. As a result, high speed and good usability of the software are achieved.

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