BEST: Binding-site Estimation Suite of Tools | Zendy

Dongsheng Che | Zendy; Scott Jensen | Zendy; Liming Cai | Zendy; Jun S. Liu | Zendy

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BEST: Binding-site Estimation Suite of Tools

Author(s) -

Dongsheng Che,

Scott Jensen,

Liming Cai,

Jun S. Liu

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti425

Subject(s) - suite , computer science , software , best practice , data mining , programming language , management , archaeology , economics , history

The purpose of our Binding-site Estimation Suite of Tools (BEST) is two-fold: to provide a platform for using and comparing different motif-finding programs for transcription factor binding site prediction, and to improve the accuracy of these predictions by further optimization. Our software package BEST includes four commonly used motif-finding programs: AlignACE, BioProspector, CONSENSUS and MEME, as well as the optimization program BioOptimizer. BEST allows the user to run programs either separately or sequentially and manages all programs by automating the common inputs and the optimization procedure. The BEST system was implemented in Qt, a C++ application development framework, and was compiled and executed on Linux operating systems.

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