ROBIN: a tool for genome rearrangement of block-interchanges
Author(s) -
C. L. Lu,
Timothy C. Wang,
Ying Lin,
Chuan Yi Tang
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti412
Subject(s) - genome , sequence (biology) , chromosome , block (permutation group theory) , computer science , chromosomal rearrangement , genetics , biology , computational biology , combinatorics , mathematics , gene , karyotype
ROBIN is a web server for analyzing genome rearrangement of block-interchanges between two chromosomal genomes. It takes two or more linear/circular chromosomes as its input, and computes the number of minimum block-interchange rearrangements between any two input chromosomes for transforming one chromosome into another and also determines an optimal scenario taking this number of rearrangements. The input can be either bacterial-size sequence data or landmark-order data. If the input is sequence data, ROBIN will automatically search for the identical landmarks that are the homologous/conserved regions shared by all the input sequences.
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