GandrKB--ontological microarray annotation and visualization | Zendy

Daniel Schober | Zendy; Ulf Leser | Zendy; Martin Zenke | Zendy; J.R. Reich | Zendy

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GandrKB--ontological microarray annotation and visualization

Author(s) -

Daniel Schober,

Ulf Leser,

Martin Zenke,

J.R. Reich

Publication year - 2005

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti401

Subject(s) - annotation , computer science , protégé , context (archaeology) , microarray databases , visualization , representation (politics) , information retrieval , microarray analysis techniques , gene , data mining , artificial intelligence , biology , semantic web , genetics , paleontology , gene expression , politics , political science , law

The Gandr (gene annotation data representation) knowledgebase is an ontological framework for laboratory-specific gene annotation. Gandr uses Protege 2000 for editing, querying and visualizing microarray data and annotations. Genes can be annotated with provided, newly created or imported ontological concepts. Annotated genes can inherit assigned concept properties and can be related to each other. The resulting knowledgebase can be visualized as interactive network of nodes and edges representing genes and their functional relationships. This allows for immediate and associative gene context exploration. Ontological query techniques allow for powerful data access.

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