Architecture of basic building blocks in protein and domain structural interaction networks | Zendy

Hichan Moon | Zendy; Jong Bhak | Zendy; K. H. Lee | Zendy; Doheon Lee | Zendy

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Architecture of basic building blocks in protein and domain structural interaction networks

Author(s) -

Hichan Moon,

Jong Bhak,

K. H. Lee,

Doheon Lee

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti240

Subject(s) - computer science , topology (electrical circuits) , domain (mathematical analysis) , interaction network , protein–protein interaction , protein domain , protein interaction networks , node (physics) , interaction information , similarity (geometry) , theoretical computer science , biological network , computational biology , artificial intelligence , biology , mathematics , physics , genetics , mathematical analysis , statistics , combinatorics , quantum mechanics , image (mathematics) , gene

The structural interaction of proteins and their domains in networks is one of the most basic molecular mechanisms for biological cells. Topological analysis of such networks can provide an understanding of and solutions for predicting properties of proteins and their evolution in terms of domains. A single paradigm for the analysis of interactions at different layers, such as domain and protein layers, is needed.

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