Quantifying the relevance of different mediators in the human immune cell network | Zendy

Paolo Tieri | Zendy; Silvana Valensin | Zendy; Vito Latora | Zendy; Gastone Castellani | Zendy; Massimo Marchiori | Zendy; Daniel Remondini | Zendy; Claudio Franceschi | Zendy

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Quantifying the relevance of different mediators in the human immune cell network

Author(s) -

Paolo Tieri,

Silvana Valensin,

Vito Latora,

Gastone Castellani,

Massimo Marchiori,

Daniel Remondini,

Claudio Franceschi

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti239

Subject(s) - relevance (law) , immune system , computer science , computational biology , biology , immunology , political science , law

Immune cells coordinate their efforts for the correct and efficient functioning of the immune system (IS). Each cell type plays a distinct role and communicates with other cell types through mediators such as cytokines, chemokines and hormones, among others, that are crucial for the functioning of the IS and its fine tuning. Nevertheless, a quantitative analysis of the topological properties of an immunological network involving this complex interchange of mediators among immune cells is still lacking.

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