Balancing protein similarity and gene co-expression reveals new links between genetic conservation and developmental diversity in invertebrates | Zendy

Christine Lefebvre | Zendy; Jean-Christophe Aude | Zendy; Hélène Glémet | Zendy; Christian Néri | Zendy

Open Access

Balancing protein similarity and gene co-expression reveals new links between genetic conservation and developmental diversity in invertebrates

Author(s) -

Christine Lefebvre,

Jean-Christophe Aude,

Hélène Glémet,

Christian Néri

Publication year - 2004

Publication title -

computer applications in the biosciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1460-2059

pISSN - 0266-7061

DOI - 10.1093/bioinformatics/bti215

Subject(s) - biology , computational biology , gene , genetic diversity , genetics , evolutionary biology , population , demography , sociology

To identify genetic conservation relative to precise aspects of developmental diversity, an essential question in computational biology, we developed a new comparative method that allows conserved modules for the best balance between protein sequence similarity and gene co-expression to be constructed, in invertebrates.

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