A score matrix to reveal the hidden links in glycans
Author(s) -
Kiyoko F. AokiKinoshita,
Hiroshi Mamitsuka,
Tatsuya Akutsu,
Minoru Kanehisa
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti193
Subject(s) - glycan , computer science , distance matrix , matrix (chemical analysis) , computational biology , tree (set theory) , biological data , variety (cybernetics) , data mining , bioinformatics , artificial intelligence , algorithm , biology , mathematics , chemistry , genetics , combinatorics , glycoprotein , chromatography
Glycans are the third major class of biomolecules following DNA and proteins. They are extremely vital for the functioning of multicellular organisms. However, comparing the fast development of sequence analysis techniques, informatics work on glycans have a long way to go. Alignment algorithms for glycan tree structures are one of the foremost concerns. In addition, the statistical analysis of these algorithms in terms of biological significance needs to be addressed.
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