Synergy of human Pol II core promoter elements revealed by statistical sequence analysis | Zendy

Naum I. Gershenzon | Zendy; I. P. Ioshikhes | Zendy

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Synergy of human Pol II core promoter elements revealed by statistical sequence analysis

Author(s) -

Naum I. Gershenzon,

I. P. Ioshikhes

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti172

Subject(s) - tata box , promoter , transcription (linguistics) , computational biology , transcription factor ii a , genetics , biology , response element , dna , general transcription factor , computer science , gene , gene expression , linguistics , philosophy

The subject of our paper is bioinformatics analysis of the distinguishing features of human promoter DNA sequences, in particular of synergetic combinations of core promoter elements therein. We suppose that specific scenarios of transcription initiation are essentially related to various particular implementations of the interaction of basal transcription machinery with promoter DNA, depending on the presence and mutual positioning of core promoter elements.

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